Endocrine Abstracts

Background: Maternal circulating cortisol and 24-h urinary free cortisol levels are up to three times higher in third trimester pregnant women compared to non-pregnant women. Maternal cortisol status could be associated with offspring sex, maternal PCOS and testosterone levels.Aims: To determine predictors of maternal serum (S) and urinary (U) cortisol and cortisone levels during 3rd trimester and to examine associations between maternal cortisol status,...

Background: Higher testosterone levels during pregnancy in women with polycystic ovary syndrome (PCOS) could be associated with longer offspring ano-genital distance (AGD).Aims: To compare AGD between offspring of mothers with PCOS and controls and to determine possible associations between maternal 3rd trimester testosterone levels and offspring AGD at three months of age.Methods: The study was part of the prospective s...

Background: Prolactin is associated with metabolic risk inside and outside of pregnancy. Maternal prolactin levels could be associated with offspring body composition.Aim: To investigate if maternal prolactin-levels were linked to offspring body composition at seven years of age.Design: Prospective observational cohort study (the Odense Child Cohort).Methods: Maternal fasting blood samples were assessed durin...

Objectives: There is limited knowledge of high-sensitivity C-reactive protein (CRP) levels among newly diagnosed T2D patients in the population-based setting, and of factors associated with elevated CRP.Methods: Measurements of CRP were performed in the first 1036 T2D patients in the nationwide DD2 project, enrolling new T2D patients from general practitioners and hospital specialist outpatient clinics. We examined the number of T2D patients within CRP t...

Objectives: Elevated levels of serum alanine aminotransferase (ALAT) have been linked with non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), insulin resistance and the metabolic syndrome in type 2 diabetes (T2D) patients. We examined ALAT levels in newly diagnosed T2D patients, and the factors associated with such elevation.Methods: Measurements of ALAT were performed in 1025 (43% women and 57% men) new T2D patients enrolle...

Few population-based data exist on the prevalence of the metabolic syndrome (MS) its components, and its association with subclinical inflammation and insulin resistance among patients newly diagnosed with type two diabetes (T2D).We examined the MS according to IDF criteria by linkage primary data (waist circumference, fasting blood glucose, and high-sensitivity C-reactive protein (CRP)) with variables from the Danish diabetes database for adults (blood ...